Fluid responsiveness in healthy volunteers: data precision and significance

Variability of aortic blood flow predicts fluid responsiveness in spontaneously breathing healthy volunteers.

BACKGROUND Assessment of fluid responsiveness is an important topic in acute cardiology. Echocardiographic measurement of respiratory variations of aortic blood velocity in ventilated shock patients can accurately predict the effect of volume expansion. On the other hand, it remains unclear whether this respiratory variability is a common physiological reaction to hypovolaemia and whether its m...

Aspirin responsiveness in healthy volunteers measured with multiple assay platforms.

BACKGROUND We evaluated the sensitivity, precision, and concordance of 4 assays designed to detect aspirin responsiveness or resistance. METHODS Twenty-nine healthy laboratory volunteers took 80 mg aspirin for 7 days, and a subset of volunteers took 325 mg aspirin for an additional 7 days. We measured platelet function by light transmission aggregometry with arachidonic acid, PFA-100, and Ver...

Spinopelvic Parameters among Healthy Volunteers in Iran

Background: Recently, in approach to spinal pathologies, the whole spine should be considered as a biomechanicalunit. Studies have shown the great importance of sagittal and coronal balance and the relationship between the variousparts of spine together and pelvis. Former studies have shown a close relationship between spinopelvic parametersand sagittal balance. A complete und...

IgA Nephropathy and Significance of Immunostaining Data

The hematologic effects of cigarette smoking in healthy men volunteers

Substances existed in tobacco smoke including carcinogens, alkaloids (mainly nicotine), irritants of the respiratory tract and carbon monoxide are known responsible for a wide range of diseases and disorders. The current study was designed to investigate the hematologic effects of smoking. This study is an observational, cross-sectional investigation in which the peripheral blood erythrocytic a...